SIFR technology

Universal. Modular. Predictive. The ex vivo SIFR^® technology pipeline simulates the entire gastrointestinal tract, from digestion through gut microbiome fermentation all the way to host interaction.

Validated to predict clinical outcomes, the SIFR^® technology pipeline relies on automation to provide robust data, supporting confident decision-making at every stage of research and development.

De-risk your product development

Biorelevance

Preserves the unicity of each individual gut microbiome, both luminal and mucosal

Validated predictivity

Forecasts clinical impact on microbial composition, metabolite profiles and health benefits

Modular design

Digestion, gut fermentation or host response – individually or in combination based on your research question

Impactful reporting

Obtain actionable insights from compelling visuals and comprehensive reporting

From early screening to in-depth characterisation

SIFR^® in screening mode

In screening mode, swiftly evaluate numerous candidates early in discovery phase and identify the most promising ones. Get quick and targeted insights into the efficacy of your products, dosing, synergies, and many more aspects.

SIFR^® in prism mode

In prism mode, characterise the interplay between your products and the gut microbiome to provide unparalleled insights into mechanisms of action, efficacy, and interindividual variations. De-risk your product development with a fully validated and predictive ex vivo simulation, increasing your chances of success at clinical stage and providing you with all the data necessary to support IP and regulatory dossier submissions.

Publications

Explore our research findings and insights into the gut microbiome. We’re committed to sharing our discoveries with the scientific community to advance knowledge in this field.